Preheat the oven to 350ยบ F and prepare a 13×9 baking dish with cooking spray.
Make the brownie mix according to the directions and stir in the walnuts, orange zest, and juice.
Pour the mixture into your prepared baking dish and drizzle on the cherry pie filling. Using a knife, swirl the cherries into the brownie mixture, then bake until a toothpick inserted into the brownies comes out clean, about 35 minutes.